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LAPAROSCOPY AND HYSTEROSCOPY

Definition and Indications
There are two types of endoscopic surgery for women, laparoscopy and hysteroscopy. Laparoscopy is the visualization of the abdominal cavity with an endoscope. Although laparoscopy was mainly a diagnostic tool in the beginning, today almost all gynecologic operations can be performed with the via this route. Hysteroscopy is the endoscopic visualization of the cavity of the uterus. Uterine abnormalities requiring open surgery in the past are easily corrected with the hysteroscope anymore.

Who is a candidate for endoscopic surgery?

Endoscopy can be performed to anybody whose general condition is suitable for surgery. As endoscopy is performed in the head down position it may not be the preferred method for those with severe respiratory or cardiac conditions. Open surgery should be preferred in women with large and numerous fibroids or ovarian carcinoma. In women with cancer of the cervix or the endometrium open surgery should be preferred if the surgeon is not experienced in oncologic endoscopic procedures.

 

What are the advantages?

Most of the operations requiring open surgery are nowadays performed with laparoscopy or the hysteroscopy   Advantage of the endoscopic technique is due to smaller incisions on the skin, the extent of the operation performed in the abdominal cavity is the same as open surgery. Patients feel less pain, stay shorter in the hospital, and return to work quicker.

 

Complications

Complications of laparoscopy

Laparoscopy is a surgical procedure and as all surgical procedures it has complications. Complications of laparoscopy are more frequent in inexperienced hands. Complications arise either during insertion of the ports (trocars) through which the instruments are introduced or while performing the surgery itself. Great vessel or bowel injuries may occur while insertion of the trocars and the telescope. During the surgery, bowel, bladder, ureter or vascular injuries may occur. Some of these complications may require conversion to open surgery for repair. Another complication of laparoscopy is conversion to open surgery due to technical impossibility of the planned laparoscopic procedure. This is usually done in the same session. When unexpected cancer is diagnosed during laparoscopy, it may be necessary to stop the operation, wake the patient and get consent for more radical surgery requiring the removal of the uterus and the ovaries.

 

Complications of hysteroscopy

Laceration of the cervix may occur during dilatation prior to insertion of the hysteroscope. The uterus may be perforated during dilatation or during the surgical procedure itself.  If the uterus is perforated the operation should be stopped and repeated in a subsequent session. If electrical energy is used for bleeding or surgery, it may cause bowel injury.  Injuries of the bladder and ureter are encountered very rarely.

LAPAROSCOPIC PROCEDURES

Laparoscopic procedures may be diagnostic or operative.  Diagnostic laparoscopy is undertaken in a patient with no positive history or physical findings.  Operative laparoscopy is performed when there is a pathology that necessitates intervention. 

 

Diagnostic laparoscopy

Popularity of diagnostic laparoscopy has decreased over the years and has become a relatively rarely performed operation.  Diagnostic laparoscopy is performed to determine the cause of infertility in a woman who has no abnormality in her medical history or physical examination. In a woman without secondary dysmenorrhea, dyspareunia, history of sexually transmitted disease (gonorrhea, chlamydial infection, etc.), previous pelvic surgery (cytectomy, myomectomy or ectopic pregnancy, etc.) or intrauterine device use, and has a normal physical exam with a normal hysterosalpingogram,   laparoscopy is not expected to yield a significant problem.  Mild endometriosis, mild intraabdominal adhesions or tubal obstruction may be diagnosed in these cases. It is extremely rare to see obstructed tubes at the time of laparoscopy in a woman with a normal hysterosalpingogram, and whenever this is encountered it is thought to be due to tubal spasm.  Whether the treatment of mild endometriosis diagnosed during laparosocopy improves infertility is debatable. The treatment should be the same as for unexplained infertility in these patients.

 

Hydrolaparoscopy is another procedure that may be regarded as diagnostic laparoscopy. It does not require general anesthesia. Sterile saline is infused to the abdominal cavity through a needle inserted from the vagina. Ovaries, tubes, uterus and pelvic peritoneum are examined. Like normal diagnostic laparoscopy, hydrolaparoscopy also provides limited information and does not change the management so its indications are also controversial.

 

Operative laparoscopy

Operative laparoscopy is performed to treat a previously diagnosed condition or to remove a diseased organ.

 

Laparoscopic procedures to increase fertility (fertility promoting laparoscopic surgery)

Adhesiolysis, salpingostomy and fimbrioplasty

 

Previous pelvic infections and pelvic surgery usually cause adhesions that impair the relationship between the tubes and the ovaries.  When the adhesions are filmy and if it is technically feasible to release them laparoscopic adhesiolysis may be beneficial. Following restoration of the normal anatomic relation between the tubes and the ovaries, pregnancy rates between 30 to 60% have been reported depending on the age of the woman and the presence of other causes for infertility. When the adhesions are dense, reformation rate following adhesiolysis is high, hence the pregnancy rates are low. Obstructed tubes may be opened by laparoscopy. Especially when the tubes are obstructed at the distal ends (on the fimbrial tip) -namely hydrosalpinges- they may be opened by a procedure called salpingostomy. Reocclusion rates vary between 30 to 100% depending on tubal wall thickness, tubal mucosal injury and the presence of surrounding adhesions.  Pregnancy rates vary between 10 to 70% depending upon the severity of the adhesions. When creating a new opening to the tubes is impossible, they must be removed so that the pregnancy rate in a subsequent in vitro fertilization treatment (IVF) is not impaired.  Leaving the obstructed tubes particularly hydrosalpinx in place decrease pregnancy rates when IVF is performed

 

Laparoscopic endometriosis surgery

Endometriosis is one of the most frequent indications for operative laparoscopy. Endometriosis is caused by implantation and growth of endometrial cells outside of the uterus. It is most frequently localized on the peritoneum (inner lining of the abdominal cavity) and  the ovaries. Additionally it may develop between the uterus and the distal portion of the bowel and cause considerable pain. In advanced stages of the disease uterus, ovaries, tubes, and the bowel may adhere to form a mass and cause pelvic pain and/or infertility. In the early stages of the disease there are small lesions on the peritoneum that resemble gunpowder spots. These lesions may be cauterized or vaporized by laser during laparoscopy.

 

In more advanced stages, cysts called endometriomas form in the ovaries. Laparoscopic removal of endometriomas increases the chances of a spontaneous conception. Preservation of ovarian reserve during laparoscopic surgery is paramount. Injury to normal ovarian tissue may occur during stripping the cyst wall that may decrease ovarian reserve. Both endometriosis per say and surgery to treat endometriosis may inevitably decrease ovarian reserve, so especially in women with recurrent endometriomas, there’s a trend towards directly proceeding to IVF instead of surgery. But if the major concern is pain, then there’s no other choice than surgery. Approximately 50% of infertile couples achieve a pregnancy in the first 6 months following surgery. IVF is necessary for couples who have still not conceived one year after surgery.

 

Laparoscopic removal of deep endometriosis located between the bowel and the uterus is possible. Removal of the lesions usually alleviates the pain. Surgical treatment of deep endometriosis takes time and requires an experienced surgeon.

 

It has to be kept in mind that endometriosis is a disease with risk of recurrence. Especially in the premenopausal period the risk of recurrence is approximately 50%. For this reason, we offer IVF to women failing to achieve a spontaneous pregnancy in a 6 months period following complete surgical removal of all endometriotic lesions. Intra uterine insemination is not offered in this context due to low pregnancy rates.

 

Laparoscopic surgery for cysts

Although endometriomas are the most common cystic lesions that are treated by laparoscopy, persistent simple cysts and dermoid cysts are also amenable to this form of treatment. Endometriomas were mentioned previously so in this section I will discuss simple cysts and dermoids.

 

 

Dermoid cysts

Dermoid cysts contain all tissue types present in the human body. Fat, hair, teeth, neural or muscular tissue may be present in dermoid cysts. They are usually formed during intrauterine life with sequestration of these tissues in the ovaries. It is not known why they continue growing in the postnatal life. They most frequently cause a complication named “ovarian torsion”. This is turning of the ovary with its neighboring tube around its axis impeding blood flow. If timely laparoscopic intervention is not performed, eventually necrosis starts in the ovary and the tube, necessitating their excision. Dermoid cysts may need to be removed if they exceed 3 to 4 centimeters in size. They are quite easily removed with laparoscopy. In 15% of the cases the contralateral ovary may be also involved necessitating careful intraoperative evaluation. There’s 1% chance that dermoids may have malignant components. Malignant dermoids contain immature neural tissue.

 

Paraovarian cysts

These are congenital remnants adjacent to the ovary. Very rarely they bear malignant potential. They must be excised if they grow big. Laparosocpic removal is an easy procedure. 

 

Cystadenomas

 

These tumors grow in the ovary and bear malignant potential. A cystadenoma is suspected when cystic and solid components are seen together in an ovarian cyst. Cyst excision is necessary for a definitive diagnosis. Cystadenomas are most frequently serous or mucinous nature. They are easily excised with laparoscopy. Removal of the ovary is a better choice for women approaching or in menopause. Ovary may be preserved in younger women but the cyst must be examined for malignancy during operation (frozen section).

 

Laparoscopic surgery for fibroids

A substantial proportion of fibroids can be removed with laparoscopy. Indications for myomectomy are as follows:

Size: Fibroids over 6 centimeters in diameter as well as rapidly enlarging fibroids should generally be removed surgically.

Bleeding: Fibroids do not cause bleeding unless they protrude to or exert pressure on the inner layer (endometrium) of the uterus. Surgery is recommended regardless of size for fibroids that protrude into endometrium and cause bleeding. The surgical method of choice in these patients is hysteroscopic myomectomy. Fibroids are removed through the cervix and vagina.

 

Symptoms of pressure: When fibroids are located between the ligaments supporting the uterus, they may occlude the ureter (tube connecting kidney and bladder). Such a fibroid must be removed. Fibroids growing in the anterior wall of the uterus may exert pressure on the bladder, while fibroids growing in the posterior wall may exert pressure on the rectum.

 

Infertility: Fibroids usually do not cause infertility. But if previous examinations fail to detect another cause for infertility then fibroids may be removed. It is generally recommended that fibroids larger than 5 centimeters should be removed. Any fibroid protruding into endometrial cavity in an infertile woman must be removed, regardless of size and the presence of other complaints.

 

Laparoscopic removal is preferred for fibroids smaller than 8 centimeters, or when number of fibroids larger than 3 centimeters is less than 3, or the fibroids are not deeply buried in the uterine tissue. Pregnancy should be avoided for 3 month following laparoscopic myomectomy. Adhesion formation following laparoscopic myomectomy is less frequent compared to open surgery. Laparoscopic myomectomy takes between 1 to 3 hours depending on the localization and the size of fibroids. Patients usually need to stay one night in the hospital after the operation.

 

Laparoscopic removal of the uterus (hysterectomy)

It is possible to remove the uterus laparoscopically. In cases of uterine descensus vaginal hysterectomy is the preferred method. Laparoscopic hysterectomy is an alternative to classical abdominal hysterectomy, a descended uterus should not be removed laparoscopically. Laparoscopic hysterectomy is a successful operation in experienced hands, and has all advantages of laparoscopy. In laparoscopic assisted vaginal hysterectomy (LAVH) the uterus is partly released with laparoscopy and is taken out through the vagina. This operation is feasible in women who had previous vaginal deliveries.  If the woman has not delivered vaginally and the uterus is big a laparosopic total hysterectomy mAy be necessary.  In this setting the uterus is completely released by laparoscopy.  It may be removed from the vagina or through the abdomen by morcellation.  Patients are usually discharged from the hospital in 1 to 2 days.  Complications of laparoscopic hysterectomy include conversion to open surgery due to technical difficulties or complications, bleeding, and injury to the blood vessels, ureter or bowel. 

 

 


HYSTEROSCOPIC PROCEDURES

Classical hysteroscopy

Hysteroscopy is visualization of the uterine cavity with an illuminated telescope. It can be diagnostic or therapeutic. Diagnostic hysteroscopy is usually performed with the office hysteroscope. Operative hysteroscopy generally requires anesthesia and an electroresectoscope is introduced to the womb following cervical dilatation. General anesthesia is usually preferred. Electroresectoscope is the instrument which urologists use for resection of the prostate. This instrument enables removal of intrauterine septa as well as fibroids or polyps. Additionally adhesions in the womb can be released. Women with excessive bleeding and do not want future pregnancies can be treated with removal of endometrial tissue with hysteroscopy. This procedure is named endometrial ablation. Scissors or laser can also be used with hysteroscopy but electric energy is the preferred method today.

 

Office hysteroscopy

 

Hysteroscopy performed in the office without anesthesia is called office hysteroscopy. Fine instruments not requiring dilatation of the cervix for introduction into the womb are used. Office hysteroscopy was used for mainly diagnostic procedures in the past but today it became possible to cure many uterine diseases with office hysteroscopy. Office hysteroscopy is most commonly used for evaluation of abnormal uterine bleeding, infertility and intrauterine adhesions. Small fibroids and polyps can be removed with office hysteroscopy. Congenital intrauterine septa can be cut or lost intrauterine devices can be removed with office hysteroscopy.

 

Office hysteroscopy is done under mild sedation without using vaginal speculum or dilating or grasping the cervix. Mild cramps may be felt during introduction of the office hysteroscope to the womb. Sterile saline is instilled into the uterine cavity and the cavity is inspected on the screen.

 

Office hysteroscopy is extremely useful for evaluation of abnormal bleeding both before and after menopause. Polyps, fibroids or tumors in the womb are easily seen with the hysteroscope. Some of them may be removed with the office hysteroscope. But some require wider hysteroscopic resection or other surgical interventions under general anesthesia.

 

Hysteroscopy is very useful for evaluation of infertility. Adhesions or masses in the womb can cause infertility and a substantial proportion of these problems can be treated with hysteroscopy. Confirmation of a normal uterine cavity, especially in women who do not have a prior hysterosalpyngogram, is important before commencement of IVF procedures. Hysteroscopy is more important for women with prior IVF failures. There are several studies demonstrating uterine abnormalities in more than 50% of women with 2 or more prior IVF failures. Endometritis, adhesions, polyps and deep septa are the most common abnormalities encountered in these women. Treatment of these abnormalities may restore IVF pregnancy rates to normal levels in these poor prognosis women.